AnkurHEALTH · specialist diagnostics

Advanced andrology diagnostics

A routine semen analysis answers a narrow question. When the answer does not fit the couple in front of us, we look further — at DNA integrity, oxidative stress and sperm function, not just count and motility.

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The principle

Comprehensive andrology diagnosis means understanding the patient and the sperm beyond the conventional parameters, when the clinical picture calls for it. Two men can have identical semen reports and entirely different problems.

That is the difference between owning a laboratory and having a diagnostic philosophy. The approach here comes out of published laboratory work — flow-cytometric assessment of sperm DNA fragmentation, specialised sperm transport media, non-cryogenic transport systems, and research into point-of-care and home-based semen assessment.

Why it changes decisions

Treatment chosen on an incomplete diagnosis is a guess with a bill attached. Establishing the underlying problem first is what makes it possible to say “you do not need this procedure” — and to mean it.

What can be assessed

The investigations

Not everyone needs all of these. Which apply depends on the history, the examination and what the first results show.

Semen and sperm function

Comprehensive semen analysis to WHO 6th edition criteria
Sperm DNA fragmentation testing
Flow-cytometry-based DNA fragmentation assessment
Reactive oxygen species (ROS)
Acrosin assessment
Annexin V and sperm apoptosis assessment
Advanced sperm functional assessment

Clinical and imaging

Hormonal evaluation relevant to male infertility
Genetic evaluation — karyotype and Y-chromosome microdeletion
Scrotal and testicular imaging, including Doppler where indicated
Specialised investigations for selected male infertility conditions

Specialised andrology testing, including DNA fragmentation index and ROS, is handled through a centralised laboratory model.

Being confirmed

Where each test is performed

Which of the above are performed within the Ankur network and which are referred to an external laboratory is being confirmed against the current service list, and will be stated test by test rather than assumed. Ask at the consultation in the meantime.

Frequently asked questions

How do I prepare for a semen analysis?

Two to five days of abstinence before the test, avoid fever or sauna in the preceding weeks, and tell us about any medication you are taking. Illness in the previous three months can affect the result, so mention it even if you feel well now.

My sperm count is low — what happens next?

One abnormal report is a flag, not a diagnosis. Sperm production varies, and a single low count can reflect a recent illness or the collection itself. We repeat the test, examine you, and look for a cause. Many causes are treatable.

What is sperm DNA fragmentation?

Damage to the genetic material inside sperm, which a standard semen analysis does not measure. It matters most in recurrent pregnancy loss and in failed IVF cycles, where the count and motility look acceptable but outcomes do not follow.

Can I give the sample at home?

Yes, if it reaches the laboratory within 30 to 45 minutes and is kept at body temperature on the way. On-site collection is more reliable because the timing and handling are controlled, which matters when the result will guide treatment.

Start with the diagnosis.

All costs are explained transparently during consultation and provided in writing before treatment is undertaken.

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